Chronic cannabis smoking-enriched oral pathobiont drives behavioral changes, macrophage infiltration, and increases β-amyloid protein production in the brain

Chronic cannabis smoking-enriched oral pathobiont drives behavioral changes, macrophage infiltration, and increases β-amyloid protein production in the brain

Background: Little is known about chronic cannabis smoking-associated oral microbiome and its effects on central nervous system (CNS) functions. Methods: In the current study, we have analyzed the saliva microbiome in individuals who chronically smoked cannabis with cannabis use disorder (n = 16) an...

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Autores principales: Zhenwu Luo, Sylvia Fitting, Catrina Robinson, Andreana Benitez, Min Li, Yongxia Wu, Xiaoyu Fu, Davide Amato, Wangbin Ning, Nicholas Funderburg, Xu Wang, Zejun Zhou, Xuezhong Yu, Amanda Wagner, Xiaomei Cong, Wanli Xu, Kendra Maas, Bethany J. Wolf, Lei Huang, Jeremy Yu, Alison Scott, Aimee Mcrae-Clark, Eric D. Hamlett, Wei Jiang
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Cannabis smoking
Oral microbiome
Actinomyces meyeri
β-amyloid
Medicine
R
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/1efa300385834349ae3f982625ed84e1
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https://doaj.org/article/1efa300385834349ae3f982625ed84e1

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