Structural basis for dolichylphosphate mannose biosynthesis

The generation of glycolipid dolichylphosphate mannose (Dol-P-Man) is a critical step for protein glycosylation and GPI anchor synthesis. Here the authors report the structure of dolichylphosphate mannose synthase in complex with bound nucleotide and donor to provide insight into the mechanism of Do...

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Autores principales: Rosaria Gandini, Tom Reichenbach, Tien-Chye Tan, Christina Divne
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/1f0af37e72ad462abf59ddbe85ae391e
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