Structural basis for dolichylphosphate mannose biosynthesis

The generation of glycolipid dolichylphosphate mannose (Dol-P-Man) is a critical step for protein glycosylation and GPI anchor synthesis. Here the authors report the structure of dolichylphosphate mannose synthase in complex with bound nucleotide and donor to provide insight into the mechanism of Do...

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Autores principales:	Rosaria Gandini, Tom Reichenbach, Tien-Chye Tan, Christina Divne
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/1f0af37e72ad462abf59ddbe85ae391e
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spelling	oai:doaj.org-article:1f0af37e72ad462abf59ddbe85ae391e2021-12-02T13:24:23ZStructural basis for dolichylphosphate mannose biosynthesis10.1038/s41467-017-00187-22041-1723https://doaj.org/article/1f0af37e72ad462abf59ddbe85ae391e2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00187-2https://doaj.org/toc/2041-1723The generation of glycolipid dolichylphosphate mannose (Dol-P-Man) is a critical step for protein glycosylation and GPI anchor synthesis. Here the authors report the structure of dolichylphosphate mannose synthase in complex with bound nucleotide and donor to provide insight into the mechanism of Dol-P-Man synthesis.Rosaria GandiniTom ReichenbachTien-Chye TanChristina DivneNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rosaria Gandini Tom Reichenbach Tien-Chye Tan Christina Divne Structural basis for dolichylphosphate mannose biosynthesis
description	The generation of glycolipid dolichylphosphate mannose (Dol-P-Man) is a critical step for protein glycosylation and GPI anchor synthesis. Here the authors report the structure of dolichylphosphate mannose synthase in complex with bound nucleotide and donor to provide insight into the mechanism of Dol-P-Man synthesis.
format	article
author	Rosaria Gandini Tom Reichenbach Tien-Chye Tan Christina Divne
author_facet	Rosaria Gandini Tom Reichenbach Tien-Chye Tan Christina Divne
author_sort	Rosaria Gandini
title	Structural basis for dolichylphosphate mannose biosynthesis
title_short	Structural basis for dolichylphosphate mannose biosynthesis
title_full	Structural basis for dolichylphosphate mannose biosynthesis
title_fullStr	Structural basis for dolichylphosphate mannose biosynthesis
title_full_unstemmed	Structural basis for dolichylphosphate mannose biosynthesis
title_sort	structural basis for dolichylphosphate mannose biosynthesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/1f0af37e72ad462abf59ddbe85ae391e
work_keys_str_mv	AT rosariagandini structuralbasisfordolichylphosphatemannosebiosynthesis AT tomreichenbach structuralbasisfordolichylphosphatemannosebiosynthesis AT tienchyetan structuralbasisfordolichylphosphatemannosebiosynthesis AT christinadivne structuralbasisfordolichylphosphatemannosebiosynthesis
_version_	1718393081177309184

Structural basis for dolichylphosphate mannose biosynthesis

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