Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures.

Vesicle fusion is an indispensable cellular process required for eukaryotic cargo delivery. The Sec/Munc18 protein Munc18c is essential for insulin-regulated trafficking of glucose transporter4 (GLUT4) vesicles to the cell surface in muscle and adipose tissue. Previously, our biophysical and structu...

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Auteurs principaux: Asma Rehman, Russell J Jarrott, Andrew E Whitten, Gordon J King, Shu-Hong Hu, Michelle P Christie, Brett M Collins, Jennifer L Martin
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/1f122e2f27a84a0b9f9201719cfb7460
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