Generation and Characterization of the <i>Drosophila melanogaster paralytic</i> Gene Knock-Out as a Model for Dravet Syndrome

Dravet syndrome is a severe rare epileptic disease caused by mutations in the <i>SCN1A</i> gene coding for the Nav1.1 protein, a voltage-gated sodium channel alpha subunit. We have made a knock-out of the <i>paralytic</i> gene, the single <i>Drosophila melanogaster</...

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Autores principales: Andrea Tapia, Carlo N. Giachello, Martina Palomino-Schätzlein, Richard A. Baines, Máximo Ibo Galindo
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/1f156631eefa4c33926b88474ef18544
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