Grb2 is regulated by foxd3 and has roles in preventing accumulation and aggregation of mutant huntingtin.
Growth factor receptor protein binding protein 2 (Grb2) is known to be associated with intracellular growth and proliferation related signaling cascades. Huntingtin (Htt), a ubiquitously expressed protein, when mutated, forms toxic intracellular aggregates - the hallmark of Huntington's disease...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2013
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/1f16f5c752b7432987ec5eed146c7f2c |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|