A Short Hairpin RNA Screen of Interferon-Stimulated Genes Identifies a Novel Negative Regulator of the Cellular Antiviral Response
ABSTRACT The type I interferon (IFN) signaling pathway restricts infection of many divergent families of RNA and DNA viruses by inducing hundreds of IFN-stimulated genes (ISGs), some of which have direct antiviral activity. We screened 813 short hairpin RNA (shRNA) constructs targeting 245 human ISG...
Enregistré dans:
| Auteurs principaux: | , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2013
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/1f4c3ee4bf064ce890295a72819b2487 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|