Supercoiling and looping promote DNA base accessibility and coordination among distant sites

DNA supercoiling can result in underwinding with negative supercoiling or overwinding with positive supercoiling of the DNA double helix. Here the authors reveal insights into the dynamic relationship between DNA supercoiling-induced sequence-dependent disruptions to base pairing, DNA looping, and t...

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Autores principales: Jonathan M. Fogg, Allison K. Judge, Erik Stricker, Hilda L. Chan, Lynn Zechiedrich
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/1f4f0343af18469b8c891040f1d4e7b1
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