Supercoiling and looping promote DNA base accessibility and coordination among distant sites

DNA supercoiling can result in underwinding with negative supercoiling or overwinding with positive supercoiling of the DNA double helix. Here the authors reveal insights into the dynamic relationship between DNA supercoiling-induced sequence-dependent disruptions to base pairing, DNA looping, and t...

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Bibliographic Details
Main Authors: Jonathan M. Fogg, Allison K. Judge, Erik Stricker, Hilda L. Chan, Lynn Zechiedrich
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/1f4f0343af18469b8c891040f1d4e7b1
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