Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells.

<h4>Background</h4>Human embryonic stem cells (hESCs) are an attractive resource for new therapeutic approaches that involve tissue regeneration. hESCs have exhibited low immunogenicity due to low levels of Mayor Histocompatibility Complex (MHC) class-I and absence of MHC class-II expres...

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Autores principales: Beatriz Suárez-Alvarez, Ramón M Rodriguez, Vincenzo Calvanese, Miguel A Blanco-Gelaz, Steve T Suhr, Francisco Ortega, Jesus Otero, Jose B Cibelli, Harry Moore, Mario F Fraga, Carlos López-Larrea
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/1f5d0587905d40d2af3ba8443f906d85
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