Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation

Abstract Folding and cellular localization of many proteins of Gram-negative bacteria rely on a network of chaperones and secretion systems. Among them is the lipase-specific foldase Lif, a membrane-bound steric chaperone that tightly binds (K D = 29 nM) and mediates folding of the lipase LipA, a vi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Aldino Viegas, Peter Dollinger, Neha Verma, Jakub Kubiak, Thibault Viennet, Claus A. M. Seidel, Holger Gohlke, Manuel Etzkorn, Filip Kovacic, Karl-Erich Jaeger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
R
Q
Acceso en línea:https://doaj.org/article/1f6b74cffdfc456e8750adee00c92bc3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!