The Impact of the HydroxyMethylCytosine epigenetic signature on DNA structure and function
We present a comprehensive, experimental and theoretical study of the impact of 5-hydroxymethylation of DNA cytosine. Using molecular dynamics, biophysical experiments and NMR spectroscopy, we found that Ten-Eleven translocation (TET) dioxygenases generate an epigenetic variant with structural and p...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/1f6de9e1bc4c478a93769f666de093a8 |
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