Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer.

The effect of blocking VEGF activity in solid tumors extends beyond inhibition of angiogenesis. However, no studies have compared the effectiveness of mechanistically different anti-VEGF inhibitors with respect to changes in tumor growth and alterations in the tumor microenvironment. In this study w...

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Auteurs principaux: Christina L Roland, Kristi D Lynn, Jason E Toombs, Sean P Dineen, D Gomika Udugamasooriya, Rolf A Brekken
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/1f8ba5d37820475c9124a92a94922d4e
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