ATRX regulates glial identity and the tumor microenvironment in IDH-mutant glioma

Abstract Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent of genetic subtype. However, the genetic differences between IDH-mutant glioma subtypes are prognostic, predictive of response to chemotherapy, an...

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Bibliographic Details
Main Authors: Husam Babikir, Lin Wang, Karin Shamardani, Francisca Catalan, Sweta Sudhir, Manish K. Aghi, David R. Raleigh, Joanna J. Phillips, Aaron A. Diaz
Format: article
Language:EN
Published: BMC 2021
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Online Access:https://doaj.org/article/1f912e20cb9c45bfa17d01103b13cc81
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