ApoE4 attenuates autophagy via FoxO3a repression in the brain

Abstract Apolipoprotein E (ApoE) plays multiple roles in lipid transport, neuronal signaling, glucose metabolism, mitochondrial function, and inflammation in the brain. It is also associated with neurodegenerative diseases, and its influence differs depending on the isoform. In particular, the ε4 al...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hee-Young Sohn, Seong-Ik Kim, Jee-Yun Park, Sung-Hye Park, Young Ho Koh, Joon Kim, Chulman Jo
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/1fe86be3dec44f429f36cd5c43667ceb
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!