A redox-neutral synthesis of ketones by coupling of alkenes and amides

Classical hydroacylation of alkenes with aldehydes is a straightforward route to ketones, however aldehyde decarbonylation is a common side-process. Here, the authors report the coupling of amides, as hydroacylating agents, and alkenes under mild, metal-free conditions to afford a wide range of keto...

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Autores principales: Jing Li, Rik Oost, Boris Maryasin, Leticia González, Nuno Maulide
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/1ff496cbc3424f78b7c966f0cbe00f52
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