Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response

Interaction between platelets and neutrophils promotes neutrophil activation. Here the authors show that neutrophils initiate the cross-talk with platelets by shuttling arachidonic acid via extracellular vesicles, which platelets convert to thromboxane A2that then elicits neutrophil activation.

Guardado en:
Detalles Bibliográficos
Autores principales: Jan Rossaint, Katharina Kühne, Jennifer Skupski, Hugo Van Aken, Mark R. Looney, Andres Hidalgo, Alexander Zarbock
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/2006c9fe4f2c454ab4c649a9b4ba6148
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!