N-acetylcholinesterase-induced apoptosis in Alzheimer's disease.
<h4>Background</h4>Alzheimer's disease (AD) involves loss of cholinergic neurons and Tau protein hyper-phosphorylation. Here, we report that overexpression of an N-terminally extended "synaptic" acetylcholinesterase variant, N-AChE-S is causally involved in both these phen...
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Auteurs principaux: | , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2008
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Accès en ligne: | https://doaj.org/article/2018499a57c049bf8580dad94ba61bb7 |
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