The genotypic and phenotypic impact of hypoxia microenvironment on glioblastoma cell lines
Abstract Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia has been shown to reprogram cells towards a stem cell phenotype associated with self-renewal and drug resistance properties. Activation of hypoxia-inducible factors (HIFs) helps in cellular adaptat...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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BMC
2021
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Acceso en línea: | https://doaj.org/article/20243c366e754f0681fc81ee1a1413ea |
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