Highly branched  poly(β-amino ester) delivery of minicircle DNA for transfection of neurodegenerative disease related cells

Therapeutics delivery by using non-viral vectors presents several challenges in the design of an appropriate polymeric structure. Here, the authors report a series of highly branched, biodegradable polymers which show high transfection efficiency in human multipotent adipose derived stem cells and p...

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Auteurs principaux: Shuai Liu, Yongsheng Gao, Dezhong Zhou, Ming Zeng, Fatma Alshehri, Ben Newland, Jing Lyu, Jonathan O’Keeffe-Ahern, Udo Greiser, Tianying Guo, Fengzhi Zhang, Wenxin Wang
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/2041b53257aa4eca91450efc3f037e8c
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