Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice

Abstract An effective vaccine would be a valuable tool for malaria control and elimination; however, the leading malaria vaccine in development, RTS,S/AS01, provided only partial protection in a Phase 3 trial. R21 is a next-generation RTS,S-like vaccine. We have previously shown in mice that R21 adm...

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Main Authors: Katharine A. Collins, Florian Brod, Rebecca Snaith, Marta Ulaszewska, Rhea J. Longley, Ahmed M. Salman, Sarah C. Gilbert, Alexandra J. Spencer, David Franco, W. Ripley Ballou, Adrian V. S. Hill
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/2049d091dd6f4297bcb5fc1522ae3a45
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