Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice
Abstract An effective vaccine would be a valuable tool for malaria control and elimination; however, the leading malaria vaccine in development, RTS,S/AS01, provided only partial protection in a Phase 3 trial. R21 is a next-generation RTS,S-like vaccine. We have previously shown in mice that R21 adm...
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Main Authors: | Katharine A. Collins, Florian Brod, Rebecca Snaith, Marta Ulaszewska, Rhea J. Longley, Ahmed M. Salman, Sarah C. Gilbert, Alexandra J. Spencer, David Franco, W. Ripley Ballou, Adrian V. S. Hill |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/2049d091dd6f4297bcb5fc1522ae3a45 |
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