A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

ABSTRACT Ebola virus (EBOV) causes highly lethal disease outbreaks against which no FDA-approved countermeasures are available. Although many host factors exploited by EBOV for cell entry have been identified, including host cell surface phosphatidylserine receptors, endosomal cysteine proteases, an...

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Autores principales: J. Maximilian Fels, Jennifer S. Spence, Robert H. Bortz, Zachary A. Bornholdt, Kartik Chandran
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/20567a5fc6a94a1da98fb64f9492e78d
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