A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

ABSTRACT Ebola virus (EBOV) causes highly lethal disease outbreaks against which no FDA-approved countermeasures are available. Although many host factors exploited by EBOV for cell entry have been identified, including host cell surface phosphatidylserine receptors, endosomal cysteine proteases, an...

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Bibliographic Details
Main Authors: J. Maximilian Fels, Jennifer S. Spence, Robert H. Bortz, Zachary A. Bornholdt, Kartik Chandran
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/20567a5fc6a94a1da98fb64f9492e78d
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