Specificity and off-target effects of AAV8-TBG viral vectors for the manipulation of hepatocellular gene expression in mice
Mice are a widely used pre-clinical model system in large part due to their potential for genetic manipulation. The ability to manipulate gene expression in specific cells under temporal control is a powerful experimental tool. The liver is central to metabolic homeostasis and a site of many disease...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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The Company of Biologists
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/20782b67b1f6464d846e370308cf1da4 |
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