The role of the e3 ligase cbl-B in murine dendritic cells.
Dendritic cells (DCs) are potent antigen-presenting cells with a promising potential in cancer immunotherapy. Cbl proteins are E3 ubiquitin ligases and have been implicated in regulating the functional activity of various immune cells. As an example, c-Cbl negatively affects DC activation. We here d...
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Main Authors: | Stephanie Wallner, Christina Lutz-Nicoladoni, Christoph H Tripp, Günther Gastl, Gottfried Baier, Josef M Penninger, Patrizia Stoitzner, Dominik Wolf |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/209bcfc1e9cd438e883ad9a9efb60cfd |
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