A Functional SNP in the Promoter of LBX1 Is Associated With the Development of Adolescent Idiopathic Scoliosis Through Involvement in the Myogenesis of Paraspinal Muscles

Previous studies have shown that LBX1 is associated with adolescent idiopathic scoliosis (AIS) in multiple populations. For the first time, rs1322330 located in the putative promoter region of LBX1 was found significantly associated with AIS in the Chinese population [p = 6.08 × 10–14, odds ratio (O...

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Autores principales: Leilei Xu, Zhenhua Feng, Zhicheng Dai, Wayne Y. W. Lee, Zhichong Wu, Zhen Liu, Xu Sun, Nelson Tang, Jack Chun-Yiu Cheng, Yong Qiu, Zezhang Zhu
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/20fc9b81b1a04d438c3e7eda83557c61
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