Discovery of New Ginsenol-Like Compounds with High Antiviral Activity

Discovery of New Ginsenol-Like Compounds with High Antiviral Activity

A number of framework amides with a ginsenol backbone have been synthesized using the Ritter reaction. We named the acetamide as Ginsamide. A method was developed for the synthesis of the corresponding amine and thioacetamide. The new compounds revealed a high activity against H1N1 influenza, which...

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Autores principales: Aleksandrina S. Volobueva, Olga I. Yarovaya, Marina V. Kireeva, Sophia S. Borisevich, Kseniya S. Kovaleva, Iliya Ya. Mainagashev, Yuri V. Gatilov, Margarita G. Ilyina, Vladimir V. Zarubaev, Nariman F. Salakhutdinov
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Ginsenol
Ginsamide
antiviral agent
surface protein
influenza
resistance
Organic chemistry
QD241-441
Acceso en línea:https://doaj.org/article/213d0b8301074d2988865ebc91dd9b70
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https://doaj.org/article/213d0b8301074d2988865ebc91dd9b70

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