Functional disease architectures reveal unique biological role of transposable elements

Functional disease architectures reveal unique biological role of transposable elements

Transposable elements (TE) make up a large component of the human genome and have been shown to contribute to human diseases. Here, Hormozdiari et al. estimate the contribution of TEs to the heritability of 41 complex traits and diseases and find enrichment of SINEs in blood traits.

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Bibliographic Details
Main Authors: Farhad Hormozdiari, Bryce van de Geijn, Joseph Nasser, Omer Weissbrod, Steven Gazal, Chelsea J. -T. Ju, Luke O’ Connor, Margaux L. A. Hujoel, Jesse Engreitz, Fereydoun Hormozdiari, Alkes L. Price
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
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Online Access:https://doaj.org/article/2162e007b86c49c889aa730a2d6a4779
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https://doaj.org/article/2162e007b86c49c889aa730a2d6a4779

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