Hydroxylation of the Acetyltransferase NAA10 Trp38 Is Not an Enzyme-Switch in Human Cells

Hydroxylation of the Acetyltransferase NAA10 Trp38 Is Not an Enzyme-Switch in Human Cells

NAA10 is a major <i>N</i>-terminal acetyltransferase (NAT) that catalyzes the cotranslational <i>N</i>-terminal (Nt-) acetylation of 40% of the human proteome. Several reports of lysine acetyltransferase (KAT) activity by NAA10 exist, but others have not been able to find any...

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Detalles Bibliográficos
Autores principales: Rasmus Ree, Karoline Krogstad, Nina McTiernan, Magnus E. Jakobsson, Thomas Arnesen
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
protein hydroxylation
protein acetylation
proteomics
POST-translational modification
<i>N</i>-terminal acetyltransferase
NAA10
Biology (General)
QH301-705.5
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/21747304c7b14645a8581653b8e78998
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https://doaj.org/article/21747304c7b14645a8581653b8e78998

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