Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil

Emerging variants of SARS-CoV-2 raise concerns about vaccine efficiency. Here, the authors present a post-hoc analysis for the ChAdOx1 nCoV-19 (AZD1222) vaccine trial in Brazil and provide efficacy against symptomatic COVID-19 caused by the Zeta (P.2) and other variants.

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Autores principales: Sue Ann Costa Clemens, Pedro M. Folegatti, Katherine R. W. Emary, Lily Yin Weckx, Jeremy Ratcliff, Sagida Bibi, Ana Verena De Almeida Mendes, Eveline Pipolo Milan, Ana Pittella, Alexandre V. Schwarzbold, Eduardo Sprinz, Parvinder K. Aley, David Bonsall, Christophe Fraser, Michelle Fuskova, Sarah C. Gilbert, Daniel Jenkin, Sarah Kelly, Simon Kerridge, Teresa Lambe, Natalie G. Marchevsky, Yama F. Mujadidi, Emma Plested, Maheshi N. Ramasamy, Peter Simmonds, Tanya Golubchik, Merryn Voysey, Andrew J. Pollard, the AMPHEUS Project, Oxford COVID Vaccine Trial Team
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2174b542d59f4531bfbfd908fa719572
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spelling oai:doaj.org-article:2174b542d59f4531bfbfd908fa7195722021-12-02T18:37:28ZEfficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil10.1038/s41467-021-25982-w2041-1723https://doaj.org/article/2174b542d59f4531bfbfd908fa7195722021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25982-whttps://doaj.org/toc/2041-1723Emerging variants of SARS-CoV-2 raise concerns about vaccine efficiency. Here, the authors present a post-hoc analysis for the ChAdOx1 nCoV-19 (AZD1222) vaccine trial in Brazil and provide efficacy against symptomatic COVID-19 caused by the Zeta (P.2) and other variants.Sue Ann Costa ClemensPedro M. FolegattiKatherine R. W. EmaryLily Yin WeckxJeremy RatcliffSagida BibiAna Verena De Almeida MendesEveline Pipolo MilanAna PittellaAlexandre V. SchwarzboldEduardo SprinzParvinder K. AleyDavid BonsallChristophe FraserMichelle FuskovaSarah C. GilbertDaniel JenkinSarah KellySimon KerridgeTeresa LambeNatalie G. MarchevskyYama F. MujadidiEmma PlestedMaheshi N. RamasamyPeter SimmondsTanya GolubchikMerryn VoyseyAndrew J. Pollardthe AMPHEUS ProjectOxford COVID Vaccine Trial TeamNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sue Ann Costa Clemens
Pedro M. Folegatti
Katherine R. W. Emary
Lily Yin Weckx
Jeremy Ratcliff
Sagida Bibi
Ana Verena De Almeida Mendes
Eveline Pipolo Milan
Ana Pittella
Alexandre V. Schwarzbold
Eduardo Sprinz
Parvinder K. Aley
David Bonsall
Christophe Fraser
Michelle Fuskova
Sarah C. Gilbert
Daniel Jenkin
Sarah Kelly
Simon Kerridge
Teresa Lambe
Natalie G. Marchevsky
Yama F. Mujadidi
Emma Plested
Maheshi N. Ramasamy
Peter Simmonds
Tanya Golubchik
Merryn Voysey
Andrew J. Pollard
the AMPHEUS Project
Oxford COVID Vaccine Trial Team
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
description Emerging variants of SARS-CoV-2 raise concerns about vaccine efficiency. Here, the authors present a post-hoc analysis for the ChAdOx1 nCoV-19 (AZD1222) vaccine trial in Brazil and provide efficacy against symptomatic COVID-19 caused by the Zeta (P.2) and other variants.
format article
author Sue Ann Costa Clemens
Pedro M. Folegatti
Katherine R. W. Emary
Lily Yin Weckx
Jeremy Ratcliff
Sagida Bibi
Ana Verena De Almeida Mendes
Eveline Pipolo Milan
Ana Pittella
Alexandre V. Schwarzbold
Eduardo Sprinz
Parvinder K. Aley
David Bonsall
Christophe Fraser
Michelle Fuskova
Sarah C. Gilbert
Daniel Jenkin
Sarah Kelly
Simon Kerridge
Teresa Lambe
Natalie G. Marchevsky
Yama F. Mujadidi
Emma Plested
Maheshi N. Ramasamy
Peter Simmonds
Tanya Golubchik
Merryn Voysey
Andrew J. Pollard
the AMPHEUS Project
Oxford COVID Vaccine Trial Team
author_facet Sue Ann Costa Clemens
Pedro M. Folegatti
Katherine R. W. Emary
Lily Yin Weckx
Jeremy Ratcliff
Sagida Bibi
Ana Verena De Almeida Mendes
Eveline Pipolo Milan
Ana Pittella
Alexandre V. Schwarzbold
Eduardo Sprinz
Parvinder K. Aley
David Bonsall
Christophe Fraser
Michelle Fuskova
Sarah C. Gilbert
Daniel Jenkin
Sarah Kelly
Simon Kerridge
Teresa Lambe
Natalie G. Marchevsky
Yama F. Mujadidi
Emma Plested
Maheshi N. Ramasamy
Peter Simmonds
Tanya Golubchik
Merryn Voysey
Andrew J. Pollard
the AMPHEUS Project
Oxford COVID Vaccine Trial Team
author_sort Sue Ann Costa Clemens
title Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
title_short Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
title_full Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
title_fullStr Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
title_full_unstemmed Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 lineages circulating in Brazil
title_sort efficacy of chadox1 ncov-19 (azd1222) vaccine against sars-cov-2 lineages circulating in brazil
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/2174b542d59f4531bfbfd908fa719572
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