Daptomycin-Resistant <named-content content-type="genus-species">Enterococcus faecalis</named-content> Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids

ABSTRACT Treatment of multidrug-resistant enterococci has become a challenging clinical problem in hospitals around the world due to the lack of reliable therapeutic options. Daptomycin (DAP), a cell membrane-targeting cationic antimicrobial lipopeptide, is the only antibiotic with in vitro bacteric...

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Auteurs principaux: Truc T. Tran, Diana Panesso, Nagendra N. Mishra, Eugenia Mileykovskaya, Ziqianq Guan, Jose M. Munita, Jinnethe Reyes, Lorena Diaz, George M. Weinstock, Barbara E. Murray, Yousif Shamoo, William Dowhan, Arnold S. Bayer, Cesar A. Arias
Format: article
Langue:EN
Publié: American Society for Microbiology 2013
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Accès en ligne:https://doaj.org/article/21935d38afa0486c929d749b8d19f88c
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