Daptomycin-Resistant <named-content content-type="genus-species">Enterococcus faecalis</named-content> Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids

ABSTRACT Treatment of multidrug-resistant enterococci has become a challenging clinical problem in hospitals around the world due to the lack of reliable therapeutic options. Daptomycin (DAP), a cell membrane-targeting cationic antimicrobial lipopeptide, is the only antibiotic with in vitro bacteric...

Full description

Saved in:
Bibliographic Details
Main Authors: Truc T. Tran, Diana Panesso, Nagendra N. Mishra, Eugenia Mileykovskaya, Ziqianq Guan, Jose M. Munita, Jinnethe Reyes, Lorena Diaz, George M. Weinstock, Barbara E. Murray, Yousif Shamoo, William Dowhan, Arnold S. Bayer, Cesar A. Arias
Format: article
Language:EN
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://doaj.org/article/21935d38afa0486c929d749b8d19f88c
Tags: Add Tag
No Tags, Be the first to tag this record!