ASB2 is a novel E3 ligase of SMAD9 required for cardiogenesis

Abstract Cardiogenesis requires the orchestrated spatiotemporal tuning of BMP signalling upon the balance between induction and counter-acting suppression of the differentiation of the cardiac tissue. SMADs are key intracellular transducers and the selective degradation of SMADs by the ubiquitin–pro...

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Autores principales: Kyung-Duk Min, Masanori Asakura, Manabu Shirai, Satoru Yamazaki, Shin Ito, Hai Ying Fu, Hiroshi Asanuma, Yoshihiro Asano, Tetsuo Minamino, Seiji Takashima, Masafumi Kitakaze
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/2198c64f663f4df99340febaa636532e
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