HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Abstract Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lymphatic dysfunction. The mechanisms that tran...

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Autores principales: Jason T. Boehme, Catherine J. Morris, Samuel R. Chiacchia, Wenhui Gong, Katherine Y. Wu, Rebecca J. Kameny, Gary W. Raff, Jeffrey R. Fineman, Emin Maltepe, Sanjeev A. Datar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/21ad722718874b2cb2712a1a9ed64d7b
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