HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Abstract Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lymphatic dysfunction. The mechanisms that tran...

Full description

Saved in:
Bibliographic Details
Main Authors: Jason T. Boehme, Catherine J. Morris, Samuel R. Chiacchia, Wenhui Gong, Katherine Y. Wu, Rebecca J. Kameny, Gary W. Raff, Jeffrey R. Fineman, Emin Maltepe, Sanjeev A. Datar
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/21ad722718874b2cb2712a1a9ed64d7b
Tags: Add Tag
No Tags, Be the first to tag this record!