NiH-catalyzed asymmetric hydroarylation of N-acyl enamines to chiral benzylamines
Chiral benzylamines are found in many pharmacologically active molecules. Here, the authors report an enantio- and regio-selective reductive hydroarylation of N-acyl enamines with a NiH/chiral bis-imidazoline catalytic system affording a range of enantioenriched benzylamines.
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/21aec21fa86f4c61be72924901c3cf28 |
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