Catalytic enantioselective addition of Grignard reagents to aromatic silyl ketimines
The stereoselective addition of Grignard reagents to ketimines is potentially a straightforward route to α-chiral amines. Here the authors report a catalytic, asymmetric Grignard addition to silyl ketimines, givingN-sulfonyl protected α-chiral silyl amines with tetrasubstituted stereocentres.
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
|
| Subjects: | |
| Online Access: | https://doaj.org/article/21be2c4928f94b7f9adb7908f0ebc4c3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!