Virus Infection, Genetic Mutations, and Prion Infection in Prion Protein Conversion
Conformational conversion of the cellular isoform of prion protein, PrP<sup>C</sup>, into the abnormally folded, amyloidogenic isoform, PrP<sup>Sc</sup>, is an underlying pathogenic mechanism in prion diseases. The diseases manifest as sporadic, hereditary, and acquired disor...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
MDPI AG
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/21c6fb74577f46fdba3cfa2a3a51263b |
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