Engineered adeno-associated virus 3 vector with reduced reactivity to serum antibodies
Abstract The natural serotypes of adeno-associated virus (AAV) or their variants, such as AAV8 and AAV5, are commonly used as vectors in the clinical programs for liver-targeted gene therapy. While AAV8 vectors are not highly efficient at targeting primary human hepatocytes, AAV3 vectors have recent...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/21dbdb3102a64787821dc94a450f9501 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|