The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts.

<h4>Background</h4>Diurnal behavior in humans is governed by the period length of a circadian clock in the suprachiasmatic nuclei of the brain hypothalamus. Nevertheless, the cell-intrinsic mechanism of this clock is present in most cells of the body. We have shown previously that for in...

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Auteurs principaux: Lucia Pagani, Ekaterina A Semenova, Ermanno Moriggi, Victoria L Revell, Lisa M Hack, Steven W Lockley, Josephine Arendt, Debra J Skene, Fides Meier, Jan Izakovic, Anna Wirz-Justice, Christian Cajochen, Oksana J Sergeeva, Sergei V Cheresiz, Konstantin V Danilenko, Anne Eckert, Steven A Brown
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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Accès en ligne:https://doaj.org/article/21e0abc2e92a485981f10ae1bc42bb7e
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