Identification and characterization of short leader and trailer RNAs synthesized by the Ebola virus RNA polymerase

Transcription of non-segmented negative sense (NNS) RNA viruses follows a stop-start mechanism and is thought to be initiated at the genome’s very 3’-end. The synthesis of short abortive leader transcripts (leaderRNAs) has been linked to transcription initiation for some NNS viruses. Here, we identi...

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Auteurs principaux: Simone Bach, Jana-Christin Demper, Paul Klemm, Julia Schlereth, Marcus Lechner, Andreas Schoen, Lennart Kämper, Friedemann Weber, Stephan Becker, Nadine Biedenkopf, Roland K. Hartmann
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/21eabf70a80a4353bb9fa60d33061d44
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