Skeletal adaptation to intramedullary pressure-induced interstitial fluid flow is enhanced in mice subjected to targeted osteocyte ablation.

Interstitial fluid flow (IFF) is a potent regulatory signal in bone. During mechanical loading, IFF is generated through two distinct mechanisms that result in spatially distinct flow profiles: poroelastic interactions within the lacunar-canalicular system, and intramedullary pressurization. While t...

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Autores principales: Ronald Y Kwon, Diana R Meays, Alexander S Meilan, Jeremiah Jones, Rosa Miramontes, Natalie Kardos, Jiunn-Chern Yeh, John A Frangos
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/21f91510f12944a69ab063e5521001fa
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