Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria.

Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria.

Platelet adhesion to the brain microvasculature has been associated with cerebral malaria (CM) in humans, suggesting that platelets play a role in the pathogenesis of this syndrome. In vitro co-cultures have shown that platelets can act as a bridge between Plasmodium falciparum-infected red blood ce...

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Main Authors: Mathieu Barbier, Dorothée Faille, Béatrice Loriod, Julien Textoris, Claire Camus, Denis Puthier, Laurence Flori, Samuel Crocodile Wassmer, Geneviève Victorero, Marie-Christine Alessi, Thierry Fusaï, Catherine Nguyen, Georges E Grau, Pascal Rihet
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/2238c69f5a2048f0baf5983c496fdbc7
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https://doaj.org/article/2238c69f5a2048f0baf5983c496fdbc7

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