Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides

Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides

Catalytic asymmetric hydrosilylation of internal alkenes has proven elusive due to more favourable double bond reduction or isomerization. Here, the authors show an enantioselective Si-C coupling by hydrosilylation of activated alkenes using a palladium/phosphoramidite catalyst affording axially chi...

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Autores principales: Xing-Wei Gu, Yu-Li Sun, Jia-Le Xie, Xing-Ben Wang, Zheng Xu, Guan-Wu Yin, Li Li, Ke-Fang Yang, Li-Wen Xu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/22450d70f92445818b71e7af0f1e2de3
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spelling oai:doaj.org-article:22450d70f92445818b71e7af0f1e2de32021-12-02T17:30:52ZStereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides10.1038/s41467-020-16716-52041-1723https://doaj.org/article/22450d70f92445818b71e7af0f1e2de32020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16716-5https://doaj.org/toc/2041-1723Catalytic asymmetric hydrosilylation of internal alkenes has proven elusive due to more favourable double bond reduction or isomerization. Here, the authors show an enantioselective Si-C coupling by hydrosilylation of activated alkenes using a palladium/phosphoramidite catalyst affording axially chiral succinimides.Xing-Wei GuYu-Li SunJia-Le XieXing-Ben WangZheng XuGuan-Wu YinLi LiKe-Fang YangLi-Wen XuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xing-Wei Gu
Yu-Li Sun
Jia-Le Xie
Xing-Ben Wang
Zheng Xu
Guan-Wu Yin
Li Li
Ke-Fang Yang
Li-Wen Xu
Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
description Catalytic asymmetric hydrosilylation of internal alkenes has proven elusive due to more favourable double bond reduction or isomerization. Here, the authors show an enantioselective Si-C coupling by hydrosilylation of activated alkenes using a palladium/phosphoramidite catalyst affording axially chiral succinimides.
format article
author Xing-Wei Gu
Yu-Li Sun
Jia-Le Xie
Xing-Ben Wang
Zheng Xu
Guan-Wu Yin
Li Li
Ke-Fang Yang
Li-Wen Xu
author_facet Xing-Wei Gu
Yu-Li Sun
Jia-Le Xie
Xing-Ben Wang
Zheng Xu
Guan-Wu Yin
Li Li
Ke-Fang Yang
Li-Wen Xu
author_sort Xing-Wei Gu
title Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
title_short Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
title_full Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
title_fullStr Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
title_full_unstemmed Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
title_sort stereospecific si-c coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/22450d70f92445818b71e7af0f1e2de3
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