Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase spindle migration and oocyte division asymmet...

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Auteurs principaux: Zhe Wei, Jessica Greaney, Wei-Guo Nicholas Loh, Hayden Anthony Homer
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/225ffd678086472ca6ac67cee6e2a022
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