Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase spindle migration and oocyte division asymmet...

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Autores principales:	Zhe Wei, Jessica Greaney, Wei-Guo Nicholas Loh, Hayden Anthony Homer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/225ffd678086472ca6ac67cee6e2a022
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spelling	oai:doaj.org-article:225ffd678086472ca6ac67cee6e2a0222021-12-02T15:39:43ZNampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry10.1038/s41467-020-17088-62041-1723https://doaj.org/article/225ffd678086472ca6ac67cee6e2a0222020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17088-6https://doaj.org/toc/2041-1723Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase spindle migration and oocyte division asymmetry by controlling spindle length.Zhe WeiJessica GreaneyWei-Guo Nicholas LohHayden Anthony HomerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhe Wei Jessica Greaney Wei-Guo Nicholas Loh Hayden Anthony Homer Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
description	Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase spindle migration and oocyte division asymmetry by controlling spindle length.
format	article
author	Zhe Wei Jessica Greaney Wei-Guo Nicholas Loh Hayden Anthony Homer
author_facet	Zhe Wei Jessica Greaney Wei-Guo Nicholas Loh Hayden Anthony Homer
author_sort	Zhe Wei
title	Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
title_short	Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
title_full	Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
title_fullStr	Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
title_full_unstemmed	Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
title_sort	nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/225ffd678086472ca6ac67cee6e2a022
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Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

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