An in situ activity assay for lysyl oxidases

To address the limitation of inability to detect lysyl oxidase enzymes (LOX) catalytic function associated with diverse disease processes, Wang et al. developed an in situ activity assay by utilizing the reactivity of hydrazides with imines and carbonyls. This assay detects the total LOX activity in...

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Autores principales: Huilei Wang, Alan Poe, Lydia Pak, Kavitha Nandakumar, Sandeep Jandu, Jochen Steppan, Reik Löser, Lakshmi Santhanam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/226aeaa38a774c2ebbf2d0e380dfffce
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