Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha

Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha

Glioblastoma (GBM) is the most common malignant primary brain tumor. Glioblastomas contain a large non-cancerous stromal compartment including various populations of tumor-associated macrophages and other myeloid cells, of which the presence was documented to correlate with malignancy and reduced su...

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Auteurs principaux: Karen De Vlaminck, Ema Romão, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A. Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi, Geert Raes
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
signal regulatory protein alpha
glioblastoma
nanobodies (VHH)
imaging
myeloid cell
SIRP alpha
Immunologic diseases. Allergy
RC581-607
Accès en ligne:https://doaj.org/article/22816153b4a84f9e978050703b2fef79
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https://doaj.org/article/22816153b4a84f9e978050703b2fef79

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