Electro-osmotic capture and ionic discrimination of peptide and protein biomarkers with FraC nanopores

Biological nanopore–based protein sequencing and recognition is challenging due to the folded structure or non-uniform charge of peptides. Here the authors show that engineered FraC nanopores can overcome these problems and recognize biomarkers in the form of oligopeptides, polypeptides and folded p...

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Auteurs principaux: Gang Huang, Kherim Willems, Misha Soskine, Carsten Wloka, Giovanni Maglia
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/229ceae5404f44ed83b8b5d44da50e41
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